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Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer
BACKGROUND: NK cells can destroy tumor cells without prior sensitization or immunization. Tumors often lose expression of MHC molecules and/or antigens. However, NK cells can lyse tumor cells in a non-MHC-restricted manner and independent of the expression of tumor-associated antigens. NK cells are...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548900/ https://ncbi.nlm.nih.gov/pubmed/26303618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0632-8 |
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