Phase I Clinical Trial of Fibronectin CH296-Stimulated T Cell Therapy in Patients with Advanced Cancer

BACKGROUND: Previous studies have demonstrated that less-differentiated T cells are ideal for adoptive T cell transfer therapy (ACT) and that fibronectin CH296 (FN-CH296) together with anti-CD3 resulted in cultured cells that contain higher amounts of less-differentiated T cells. In this phase I cli...

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Hlavní autoři: Ishikawa, Takeshi, Kokura, Satoshi, Enoki, Tatsuji, Sakamoto, Naoyuki, Okayama, Tetsuya, Ideno, Mitsuko, Mineno, Junichi, Uno, Kazuko, Yoshida, Naohisa, Kamada, Kazuhiro, Katada, Kazuhiro, Uchiyama, Kazuhiko, Handa, Osamu, Takagi, Tomohisa, Konishi, Hideyuki, Yagi, Nobuaki, Naito, Yuji, Itoh, Yoshito, Yoshikawa, Toshikazu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908868/
https://ncbi.nlm.nih.gov/pubmed/24497917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083786
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