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Coordinated Regulation of Nrf2 and Histone H3 Serine 10 Phosphorylation in Arsenite-activated Transcription of the Human Heme Oxygenase-1 Gene
Expression of the antioxidant gene heme oxygenase-1 (HO-1) is primarily induced through NFE2-related factor 2 (Nrf2)-mediated activation of the antioxidant response element (ARE). Gene transcription is coordinately regulated by transcription factor activity at enhancer elements and epigenetic altera...
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Publié dans: | Biochim Biophys Acta |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548837/ https://ncbi.nlm.nih.gov/pubmed/26291278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2015.08.004 |
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