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Coordinated Regulation of Nrf2 and Histone H3 Serine 10 Phosphorylation in Arsenite-activated Transcription of the Human Heme Oxygenase-1 Gene

Expression of the antioxidant gene heme oxygenase-1 (HO-1) is primarily induced through NFE2-related factor 2 (Nrf2)-mediated activation of the antioxidant response element (ARE). Gene transcription is coordinately regulated by transcription factor activity at enhancer elements and epigenetic altera...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Ray, Paul D., Huang, Bo-Wen, Tsuji, Yoshiaki
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548837/
https://ncbi.nlm.nih.gov/pubmed/26291278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2015.08.004
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