Nalaganje...
NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function
NF-κB is generally believed to be pro-tumorigenic. Here, we report a tumor-suppressive function for NF-κB1, the prototypical member of NF-κB. While NF-κB1 down-regulation is associated with high lung cancer risk in humans and poor patient survival, NF-κB1 deficient mice are more vulnerable to lung t...
Shranjeno v:
| izdano v: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548811/ https://ncbi.nlm.nih.gov/pubmed/26300007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.299 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|