Unbalanced upregulation of ryanodine receptor 2 plays a particular role in early development of daunorubicin cardiomyopathy

Calcium release channel on the sarcoplasmic reticulum of cardiomyocytes (ryanodine receptor type 2, RyR2) plays a critical role in the regulation of calcium and was identified as a crucial factor for development of chronic anthracycline cardiomyopathy. Its early stages are less well described althou...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Kucerova, Dana, Doka, Gabriel, Kruzliak, Peter, Turcekova, Katarina, Kmecova, Jana, Brnoliakova, Zuzana, Kyselovic, Jan, Kirchhefer, Uwe, Müller, Frank U, Krenek, Peter, Boknik, Peter, Klimas, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548320/
https://ncbi.nlm.nih.gov/pubmed/26328012
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