Perinatally administered losartan augments renal ACE2 expression but not cardiac or renal Mas receptor in spontaneously hypertensive rats

Since the identification of the alternative angiotensin converting enzyme (ACE)2/Ang-(1-7)/Mas receptor axis, renin-angiotensin system (RAS) is a new complex target for a pharmacological intervention. We investigated the expression of RAS components in the heart and kidney during the development of...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Klimas, Jan, Olvedy, Michael, Ochodnicka-Mackovicova, Katarina, Kruzliak, Peter, Cacanyiova, Sona, Kristek, Frantisek, Krenek, Peter, Ochodnicky, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549047/
https://ncbi.nlm.nih.gov/pubmed/25766467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12573
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