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Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization
The assembly of spliceosomal U snRNPs depends on the coordinated action of PRMT5 and SMN complexes in vivo. These trans-acting factors enable the faithful delivery of seven Sm proteins onto snRNA and the formation of the common core of snRNPs. To gain mechanistic insight into their mode of action, w...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547896/ https://ncbi.nlm.nih.gov/pubmed/26069323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490350 |
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