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Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization

The assembly of spliceosomal U snRNPs depends on the coordinated action of PRMT5 and SMN complexes in vivo. These trans-acting factors enable the faithful delivery of seven Sm proteins onto snRNA and the formation of the common core of snRNPs. To gain mechanistic insight into their mode of action, w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Neuenkirchen, Nils, Englbrecht, Clemens, Ohmer, Jürgen, Ziegenhals, Thomas, Chari, Ashwin, Fischer, Utz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547896/
https://ncbi.nlm.nih.gov/pubmed/26069323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490350
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