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Not4-dependent translational repression is important for cellular protein homeostasis in yeast
Translation of aberrant or problematic mRNAs can cause ribosome stalling which leads to the production of truncated or defective proteins. Therefore, cells evolved cotranslational quality control mechanisms that eliminate these transcripts and target arrested nascent polypeptides for proteasomal deg...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley & Sons, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547895/ https://ncbi.nlm.nih.gov/pubmed/25971775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490194 |
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