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Not4-dependent translational repression is important for cellular protein homeostasis in yeast

Translation of aberrant or problematic mRNAs can cause ribosome stalling which leads to the production of truncated or defective proteins. Therefore, cells evolved cotranslational quality control mechanisms that eliminate these transcripts and target arrested nascent polypeptides for proteasomal deg...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Preissler, Steffen, Reuther, Julia, Koch, Miriam, Scior, Annika, Bruderek, Michael, Frickey, Tancred, Deuerling, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547895/
https://ncbi.nlm.nih.gov/pubmed/25971775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490194
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