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Directed PCR-free engineering of highly repetitive DNA sequences

BACKGROUND: Highly repetitive nucleotide sequences are commonly found in nature e.g. in telomeres, microsatellite DNA, polyadenine (poly(A)) tails of eukaryotic messenger RNA as well as in several inherited human disorders linked to trinucleotide repeat expansions in the genome. Therefore, studying...

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Bibliographic Details
Main Authors: Scior, Annika, Preissler, Steffen, Koch, Miriam, Deuerling, Elke
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187725/
https://ncbi.nlm.nih.gov/pubmed/21943395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-87
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