Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid

The activation of sterol regulatory element binding proteins (SREBPs) is regulated by insulin-induced genes-1 and -2 (Insig-1 and Insig-2) and SCAP. We previously reported that feeding R-α-lipoic acid (LA) to Zucker Diabetic Fatty (ZDF) rats improves severe hypertriglyceridemia. In this study, we in...

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Detaylı Bibliyografya
Yayımlandı:J Nutr Biochem
Asıl Yazarlar: Tong, Xuedong, Christian, Patricia, Zhao, Miaoyun, Wang, Hai, Moreau, Regis, Su, Qiaozhu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547883/
https://ncbi.nlm.nih.gov/pubmed/26007286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2015.03.011
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