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Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid
The activation of sterol regulatory element binding proteins (SREBPs) is regulated by insulin-induced genes-1 and -2 (Insig-1 and Insig-2) and SCAP. We previously reported that feeding R-α-lipoic acid (LA) to Zucker Diabetic Fatty (ZDF) rats improves severe hypertriglyceridemia. In this study, we in...
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| Publicado no: | J Nutr Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547883/ https://ncbi.nlm.nih.gov/pubmed/26007286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2015.03.011 |
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