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Restricted Replication of the Live Attenuated Influenza A Virus Vaccine during Infection of Primary Differentiated Human Nasal Epithelial Cells

Live Attenuated Influenza Vaccine (LAIV) strains are associated with cold adapted, temperature sensitive and attenuated phenotypes that have been studied in non-human or immortalized cell cultures as well as in animal models. Using a primary, differentiated human nasal epithelial cell (hNEC) culture...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Fischer, William A., King, Landon S., Lane, Andrew P., Pekosz, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547880/
https://ncbi.nlm.nih.gov/pubmed/26196325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.07.023
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