The M2 protein of live, attenuated influenza vaccine encodes a mutation that reduces replication in human nasal epithelial cells

The influenza A virus components of the live, attenuated influenza vaccine (LAIV) encode the HA and NA gene segments from a circulating virus strain and the remaining gene segments from the cold-adapted master donor virus, A/Ann Arbor/6/1960 (H2N2). The master donor virus imparts at least three phen...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Wohlgemuth, Nicholas, Ye, Yang, Fenstermacher, Katherine J., Liu, Hsuan, Lane, Andrew P., Pekosz, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696008/
https://ncbi.nlm.nih.gov/pubmed/29079099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.10.018
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