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Extensive mapping of an innate immune network with CRISPR

The application of the CRISPR-Cas9 system marks a major breakthrough for genetic screens, particularly in mammalian cells where high-throughput targeted gene editing has been lacking. Parnas et al (2015) apply this screening technology to mouse bone marrow-derived dendritic cells in order to study t...

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Dades bibliogràfiques
Publicat a:Mol Syst Biol
Autors principals: Aregger, Michael, Hart, Traver, Moffat, Jason
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547849/
https://ncbi.nlm.nih.gov/pubmed/26208794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156373
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