Single-Cell Genetic Analysis Using Automated Microfluidics to Resolve Somatic Mosaicism

Somatic mosaicism occurs throughout normal development and contributes to numerous disease etiologies, including tumorigenesis and neurological disorders. Intratumor genetic heterogeneity is inherent to many cancers, creating challenges for effective treatments. Unfortunately, analysis of bulk DNA m...

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Опубликовано в: :PLoS One
Главные авторы: Szulwach, Keith E., Chen, Peilin, Wang, Xiaohui, Wang, Jing, Weaver, Lesley S., Gonzales, Michael L., Sun, Gang, Unger, Marc A., Ramakrishnan, Ramesh
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547741/
https://ncbi.nlm.nih.gov/pubmed/26302375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135007
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