SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1

Acute Lymphoblastic Leukemia (ALL) is the most frequent childhood malignancy. In the effort to find new anti-leukemic agents, we evaluated the small drug SB225002 (N-(2-hydroxy-4-nitrophenyl)-N’-(2-bromophenyl)urea). Although initially described as a selective antagonist of CXCR2, later studies have...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: de Vasconcellos, Jaíra Ferreira, Laranjeira, Angelo Brunelli Albertoni, Leal, Paulo C., Bhasin, Manoj K., Zenatti, Priscila Pini, Nunes, Ricardo J., Yunes, Rosendo A., Nowill, Alexandre E., Libermann, Towia A., Zerbini, Luiz Fernando, Yunes, José Andrés
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547718/
https://ncbi.nlm.nih.gov/pubmed/26302043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134783
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы