Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis

Natural product curcumin (Cur) and H(2)S-releasing prodrug SH-aspirin (SH-ASA) are potential anticancer agents with diverse mechanisms, but their clinical application prospects are restricted by hydrophobicity and limited efficiency. In this work, we coencapsulated SH-ASA and Cur into methoxy poly(e...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Zhou, Lin, Duan, Xingmei, Zeng, Shi, Men, Ke, Zhang, Xueyan, Yang, Li, Li, Xiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547632/
https://ncbi.nlm.nih.gov/pubmed/26316750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S84326
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