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Enantioselective Conjugate Additions of α-Amino Radicals via Cooperative Photoredox and Lewis Acid Catalysis

[Image: see text] We report the highly enantioselective addition of photogenerated α-amino radicals to Michael acceptors. This method features a dual-catalyst protocol that combines transition metal photoredox catalysis with chiral Lewis acid catalysis. The combination of these two powerful modes of...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Espelt, Laura Ruiz, McPherson, Iain S., Wiensch, Eric M., Yoon, Tehshik P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547529/
https://ncbi.nlm.nih.gov/pubmed/25668687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja512746q
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