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Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer()

Non–small cell lung cancer (NSCLC) patients have very low survival rates because the current therapeutic strategies are not fully effective. Although EGFR tyrosine kinase inhibitors are effective for NSCLC patients harboring EGFR mutations, patients invariably develop resistance to these agents. Alt...

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Publicat a:Neoplasia
Autors principals: Bora-Singhal, Namrata, Perumal, Deepak, Nguyen, Jonathan, Chellappan, Srikumar
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547412/
https://ncbi.nlm.nih.gov/pubmed/26297432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.07.001
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