Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer()

Non–small cell lung cancer (NSCLC) patients have very low survival rates because the current therapeutic strategies are not fully effective. Although EGFR tyrosine kinase inhibitors are effective for NSCLC patients harboring EGFR mutations, patients invariably develop resistance to these agents. Alt...

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Vydáno v:Neoplasia
Hlavní autoři: Bora-Singhal, Namrata, Perumal, Deepak, Nguyen, Jonathan, Chellappan, Srikumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547412/
https://ncbi.nlm.nih.gov/pubmed/26297432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.07.001
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