Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

Primary aldosteronism (PA) represents the most common cause of secondary hypertension, but little is known regarding its adrenal cellular origins. Recently, aldosterone-producing cell clusters (APCCs) with high expression of aldosterone synthase (CYP11B2) were found in both normal and PA adrenal tis...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nishimoto, Koshiro, Tomlins, Scott A., Kuick, Rork, Cani, Andi K., Giordano, Thomas J., Hovelson, Daniel H., Liu, Chia-Jen, Sanjanwala, Aalok R., Edwards, Michael A., Gomez-Sanchez, Celso E., Nanba, Kazutaka, Rainey, William E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547250/
https://ncbi.nlm.nih.gov/pubmed/26240369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505529112
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars