Aldosterone-stimulating somatic gene mutations are common in normal adrenal glands

Primary aldosteronism (PA) represents the most common cause of secondary hypertension, but little is known regarding its adrenal cellular origins. Recently, aldosterone-producing cell clusters (APCCs) with high expression of aldosterone synthase (CYP11B2) were found in both normal and PA adrenal tis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nishimoto, Koshiro, Tomlins, Scott A., Kuick, Rork, Cani, Andi K., Giordano, Thomas J., Hovelson, Daniel H., Liu, Chia-Jen, Sanjanwala, Aalok R., Edwards, Michael A., Gomez-Sanchez, Celso E., Nanba, Kazutaka, Rainey, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547250/
https://ncbi.nlm.nih.gov/pubmed/26240369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505529112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados