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Potassium channels related to primary aldosteronism: expression similarities and differences between human and rat adrenals
Three potassium channels have been associated with primary aldosteronism (PA) in rodents and humans: KCNK3 (TASK-1), KCNK9 (TASK-3), and KCNJ5 (Kir3.4). Mice with deficiency in Kcnk3 and Kcnk9 have elevated aldosterone production and blood pressure. In humans, adrenal tumors with somatic mutations i...
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Publicado no: | Mol Cell Endocrinol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646165/ https://ncbi.nlm.nih.gov/pubmed/26375812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.09.011 |
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