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Potassium channels related to primary aldosteronism: expression similarities and differences between human and rat adrenals
Three potassium channels have been associated with primary aldosteronism (PA) in rodents and humans: KCNK3 (TASK-1), KCNK9 (TASK-3), and KCNJ5 (Kir3.4). Mice with deficiency in Kcnk3 and Kcnk9 have elevated aldosterone production and blood pressure. In humans, adrenal tumors with somatic mutations i...
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| Gepubliceerd in: | Mol Cell Endocrinol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646165/ https://ncbi.nlm.nih.gov/pubmed/26375812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.09.011 |
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