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Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy
Genome instability, primarily caused by faulty DNA repair mechanisms, drives tumorigenesis. Therapeutic interventions that exploit deregulated DNA repair in cancer have made considerable progress by targeting tumor-specific alterations of DNA repair factors, which either induces synthetic lethality...
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| Pubblicato in: | Mol Cells |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Korean Society for Molecular and Cellular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546938/ https://ncbi.nlm.nih.gov/pubmed/26194820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0175 |
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