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The Fanconi anemia pathway and ICL repair: implications for cancer therapy
Fanconi anemia (FA) is an inherited disease caused by mutations in at least 13 genes and characterized by genomic instability. In addition to displaying strikingly heterogenous clinical phenotypes, FA patients are exquisitely sensitive to treatments with crosslinking agents that create interstrand c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3108053/ https://ncbi.nlm.nih.gov/pubmed/20807115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2010.502166 |
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