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Mtor-Fanconi Anemia DNA Damage Repair Pathway in Cancer

mTOR is a serine/threonine kinase and plays a critical role in mammalian cell growth, survival, and metabolism. mTOR is present in two cellular complexes: mTORC1 and mTORC2. Dysregulation of the mTOR pathway has been related to tumorigenesis, poor prognosis and/or chemotherapy resistance in a variet...

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Detalhes bibliográficos
Publicado no:J Oncobiomarkers
Autor principal: Guo, Fukun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303082/
https://ncbi.nlm.nih.gov/pubmed/25621286
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