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Salmonella Typhimurium Co-opts the Host Type I Interferon System to Restrict Macrophage Innate Immune Transcriptional Responses Selectively

Innate immune inflammatory responses are subject to complex layers of negative regulation at intestinal mucosal surfaces. While the type I interferon (IFN) system is critical for amplifying anti-viral immunity, it has been shown to play a homeostatic role in some models of autoimmune inflammation. T...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Perkins, Darren J., Rajaiah, Rajesh, Tennant, Sharon M., Ramachandran, Girish, Higginson, Ellen E., Dyson, Tristan N., Vogel, Stefanie N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546913/
https://ncbi.nlm.nih.gov/pubmed/26202980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500105
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