Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites.
In vitro site-directed mutagenesis was used to replace individually the three known autophosphorylation sites of the epidermal growth factor (EGF)-receptor (i.e. Tyr1173, Tyr1148 and Tyr1068) by phenylalanine, a residue which cannot serve as a phosphate acceptor site. In another mutant, Tyr1173 was...
Kaydedildi:
| Yayımlandı: | EMBO J |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
1988
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3263271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03169.x |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|
