Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites.

In vitro site-directed mutagenesis was used to replace individually the three known autophosphorylation sites of the epidermal growth factor (EGF)-receptor (i.e. Tyr1173, Tyr1148 and Tyr1068) by phenylalanine, a residue which cannot serve as a phosphate acceptor site. In another mutant, Tyr1173 was...

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Bibliografske podrobnosti

izdano v:	EMBO J
Principais autores:	Honegger, A, Dull, T J, Bellot, F, Van Obberghen, E, Szapary, D, Schmidt, A, Ullrich, A, Schlessinger, J
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 1988
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3263271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03169.x
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