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Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates

Trifluoroethylarenes are found in a variety of biologically active molecules, and strategies for accessing this substructure are important for developing therapeutic candidates and biological probes. Trifluoroethylarenes can be directly accessed via nucleophilic trifluoromethylation of benzylic elec...

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Detalles Bibliográficos
Publicado en:J Org Chem
Main Authors: Ambler, Brett R., Zhu, Lingui, Altman, Ryan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546558/
https://ncbi.nlm.nih.gov/pubmed/26225803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b01343
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