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Ligand-controlled Regioselective Cu-Catalyzed Trifluoromethylation to Generate Trifluoromethylallenes

“Cu–CF(3)” species have been used historically for a broad spectrum of nucleophilic trifluoromethylation reactions. Although recent advancements have employed ligands to stabilize and harness the reactivity of this key organometallic intermediate, the ability of a ligand to differentiate a regiochem...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Ambler, Brett R., Peddi, Santosh, Altman, Ryan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433581/
https://ncbi.nlm.nih.gov/pubmed/25910053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b01027
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