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Copper-Catalyzed Synthesis of Trifluoroethylarenes from Benzylic Bromodifluoroacetates

Trifluoroethylarenes are found in a variety of biologically active molecules, and strategies for accessing this substructure are important for developing therapeutic candidates and biological probes. Trifluoroethylarenes can be directly accessed via nucleophilic trifluoromethylation of benzylic elec...

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Bibliografiske detaljer
Udgivet i:J Org Chem
Main Authors: Ambler, Brett R., Zhu, Lingui, Altman, Ryan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546558/
https://ncbi.nlm.nih.gov/pubmed/26225803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.5b01343
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