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Neurochemical metabolomics reveals disruption to sphingolipid metabolism following chronic haloperidol administration

Haloperidol is an effective antipsychotic drug for treatment of schizophrenia, but prolonged use can lead to debilitating side effects. To better understand the effects of long-term administration, we measured global metabolic changes in mouse brain following 3 mg/kg/day haloperidol for 28 days. The...

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Vydáno v:J Neuroimmune Pharmacol
Hlavní autoři: McClay, Joseph L., Vunck, Sarah A., Batman, Angela M., Crowley, James J., Vann, Robert E., Beardsley, Patrick M., van den Oord, Edwin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546545/
https://ncbi.nlm.nih.gov/pubmed/25850894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-015-9605-1
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