IPP51, a chalcone acting as a microtubule inhibitor with in vivo antitumor activity against bladder carcinoma

We previously identified 1-(2,4-dimethoxyphenyl)-3-(1-methylindolyl) propenone (IPP51), a new chalcone derivative that is capable of inducing prometaphase arrest and subsequent apoptosis of bladder cancer cells. Here, we demonstrate that IPP51 selectively inhibits proliferation of tumor-derived cell...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Martel-Frachet, Véronique, Keramidas, Michelle, Nurisso, Alessandra, DeBonis, Salvatore, Rome, Claire, Coll, Jean-Luc, Boumendjel, Ahcène, Skoufias, Dimitrios A., Ronot, Xavier
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546496/
https://ncbi.nlm.nih.gov/pubmed/26036640
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