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EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway

The role of epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) in osteosarcoma remains unknown. Then applying EFEMP1 siRNA, plasmids transfection and adding purified EFEMP1 protein in human osteosarcoma cell lines, and using immunohistochemistry on 113 osteosarcom...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Zhuo, Cao, Chuang-Jie, Huang, Lei-Lei, Ke, Zun-Fu, Luo, Can-Jiao, Lin, Zhong-Wei, Wang, Fen, Zhang, Yuan-Qi, Wang, Lian-Tang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546460/
https://ncbi.nlm.nih.gov/pubmed/25987128
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