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NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment

Tolerogenic dendritic cells (tDCs) may offer an intervention therapy in autoimmune diseases or transplantation. Stable immaturity and tolerogenic function of tDCs after encountering inflammatory environment are prerequisite for positive outcome of immunotherapy. However, the signaling pathways regul...

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Publicat a:Oncotarget
Autors principals: Dáňová, Klára, Klapetková, Anna, Kayserová, Jana, Šedivá, Anna, Špíšek, Radek, Jelínková, Lenka Palová
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546455/
https://ncbi.nlm.nih.gov/pubmed/26053099
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