NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment

Tolerogenic dendritic cells (tDCs) may offer an intervention therapy in autoimmune diseases or transplantation. Stable immaturity and tolerogenic function of tDCs after encountering inflammatory environment are prerequisite for positive outcome of immunotherapy. However, the signaling pathways regul...

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發表在:Oncotarget
Main Authors: Dáňová, Klára, Klapetková, Anna, Kayserová, Jana, Šedivá, Anna, Špíšek, Radek, Jelínková, Lenka Palová
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
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Research Paper: Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546455/
https://ncbi.nlm.nih.gov/pubmed/26053099
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