NF-κB, p38 MAPK, ERK1/2, mTOR, STAT3 and increased glycolysis regulate stability of paricalcitol/dexamethasone-generated tolerogenic dendritic cells in the inflammatory environment

Tolerogenic dendritic cells (tDCs) may offer an intervention therapy in autoimmune diseases or transplantation. Stable immaturity and tolerogenic function of tDCs after encountering inflammatory environment are prerequisite for positive outcome of immunotherapy. However, the signaling pathways regul...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Dáňová, Klára, Klapetková, Anna, Kayserová, Jana, Šedivá, Anna, Špíšek, Radek, Jelínková, Lenka Palová
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Research Paper: Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546455/
https://ncbi.nlm.nih.gov/pubmed/26053099
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