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Short-term high glucose exposure impairs insulin signaling in endothelial cells

BACKGROUND: Hyperglycemia is the hallmark of diabetes and its cardiovascular complications. Insulin plays an important role in the regulation of vascular homeostasis and maintenance of endothelial function. Insulin signaling occurs after binding to the insulin receptor, causing activation of two sep...

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書目詳細資料
發表在:Cardiovasc Diabetol
Main Authors: De Nigris, Valeria, Pujadas, Gemma, La Sala, Lucia, Testa, Roberto, Genovese, Stefano, Ceriello, Antonio
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546318/
https://ncbi.nlm.nih.gov/pubmed/26297582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0278-0
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