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Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells
BACKGROUND: Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Although oscillating glucose can induce a more deleterious effect than high glucos...
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| Publicado no: | Cardiovasc Diabetol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852407/ https://ncbi.nlm.nih.gov/pubmed/27137793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0390-9 |
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