Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface

The widespread distribution of lentiviruses among African primates, and the lack of severe pathogenesis in many of these natural reservoirs, are taken as evidence for long-term co-evolution between the simian immunodeficiency viruses (SIVs) and their primate hosts. Evidence for positive selection ac...

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Publicado en:PLoS Pathog
Main Authors: McCarthy, Kevin R., Kirmaier, Andrea, Autissier, Patrick, Johnson, Welkin E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546234/
https://ncbi.nlm.nih.gov/pubmed/26291613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005085
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