Inhibition by stabilization: targeting the Plasmodium falciparum aldolase–TRAP complex

BACKGROUND: Emerging resistance of the malaria parasite Plasmodium to current therapies underscores the critical importance of exploring novel strategies for disease eradication. Plasmodium species are obligate intracellular protozoan parasites. They rely on an unusual form of substrate-dependent mo...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Nemetski, Sondra Maureen, Cardozo, Timothy J, Bosch, Gundula, Weltzer, Ryan, O’Malley, Kevin, Ejigiri, Ijeoma, Kumar, Kota Arun, Buscaglia, Carlos A, Nussenzweig, Victor, Sinnis, Photini, Levitskaya, Jelena, Bosch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545932/
https://ncbi.nlm.nih.gov/pubmed/26289816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0834-9
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