Inhibition by stabilization: targeting the Plasmodium falciparum aldolase–TRAP complex

BACKGROUND: Emerging resistance of the malaria parasite Plasmodium to current therapies underscores the critical importance of exploring novel strategies for disease eradication. Plasmodium species are obligate intracellular protozoan parasites. They rely on an unusual form of substrate-dependent mo...

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Bibliografiske detaljer
Udgivet i:Malar J
Main Authors: Nemetski, Sondra Maureen, Cardozo, Timothy J, Bosch, Gundula, Weltzer, Ryan, O’Malley, Kevin, Ejigiri, Ijeoma, Kumar, Kota Arun, Buscaglia, Carlos A, Nussenzweig, Victor, Sinnis, Photini, Levitskaya, Jelena, Bosch, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545932/
https://ncbi.nlm.nih.gov/pubmed/26289816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0834-9
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