Inhibition by stabilization: targeting the Plasmodium falciparum aldolase–TRAP complex

BACKGROUND: Emerging resistance of the malaria parasite Plasmodium to current therapies underscores the critical importance of exploring novel strategies for disease eradication. Plasmodium species are obligate intracellular protozoan parasites. They rely on an unusual form of substrate-dependent mo...

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Detalles Bibliográficos
Publicado en:Malar J
Autores principales: Nemetski, Sondra Maureen, Cardozo, Timothy J, Bosch, Gundula, Weltzer, Ryan, O’Malley, Kevin, Ejigiri, Ijeoma, Kumar, Kota Arun, Buscaglia, Carlos A, Nussenzweig, Victor, Sinnis, Photini, Levitskaya, Jelena, Bosch, Jürgen
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545932/
https://ncbi.nlm.nih.gov/pubmed/26289816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0834-9
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