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Structure-based Design of Novel Small-Molecule Inhibitors of Plasmodium falciparum

Malaria is endemic in most developing countries, with nearly 500 million cases estimated to occur each year. The need to design a new generation of antimalarial drugs that can combat the most drug-resistant forms of the malarial parasite is well recognized. In this study, we wanted to develop inhibi...

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Detalhes bibliográficos
Main Authors: Kortagere, Sandhya, Welsh, William J., Morrisey, Joanne M., Daly, Thomas, Ejigiri, Ijeoma, Sinnis, Photini, Vaidya, Akhil B., Bergman, Lawrence W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881581/
https://ncbi.nlm.nih.gov/pubmed/20426475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci100039k
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