In vivo retention and bioactivity of IL-1ra microspheres in the rat intervertebral disc: a preliminary investigation

BACKGROUND: Inflammatory cytokines such as interleukin-1 beta (IL-1β) contribute to the progression of intervertebral disc degeneration. Previously we demonstrated, in vitro, that by delivering interleukin-1 receptor antagonist (IL-1ra) from poly(lactic co-glycolic acid) (PLGA) microspheres, we coul...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Orthop
Main Authors: Gorth, Deborah J, Martin, John T, Dodge, George R, Elliott, Dawn M, Malhotra, Neil R, Mauck, Robert L, Smith, Lachlan J
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2014
Teme:
Short Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545798/
https://ncbi.nlm.nih.gov/pubmed/26914760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-014-0015-8
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki