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In vivo retention and bioactivity of IL-1ra microspheres in the rat intervertebral disc: a preliminary investigation
BACKGROUND: Inflammatory cytokines such as interleukin-1 beta (IL-1β) contribute to the progression of intervertebral disc degeneration. Previously we demonstrated, in vitro, that by delivering interleukin-1 receptor antagonist (IL-1ra) from poly(lactic co-glycolic acid) (PLGA) microspheres, we coul...
Gorde:
| Argitaratua izan da: | J Exp Orthop |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Berlin Heidelberg
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545798/ https://ncbi.nlm.nih.gov/pubmed/26914760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-014-0015-8 |
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