A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration

OBJECTIVE: The objective of this study was to establish a large animal model that recapitulates the spectrum of intervertebral disc degeneration that occurs in humans and which is suitable for pre-clinical evaluation of a wide range of experimental therapeutics. DESIGN: Degeneration was induced in t...

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Gepubliceerd in:Osteoarthritis Cartilage
Hoofdauteurs: Gullbrand, Sarah E., Malhotra, Neil R., Schaer, Thomas P., Zawacki, Zosia, Martin, John T., Bendigo, Justin R., Milby, Andrew H., Dodge, George R., Vresilovic, Edward J., Elliott, Dawn M., Mauck, Robert L., Smith, Lachlan J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182186/
https://ncbi.nlm.nih.gov/pubmed/27568573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.08.006
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