A Large Animal Model that Recapitulates the Spectrum of Human Intervertebral Disc Degeneration

OBJECTIVE: The objective of this study was to establish a large animal model that recapitulates the spectrum of intervertebral disc degeneration that occurs in humans and which is suitable for pre-clinical evaluation of a wide range of experimental therapeutics. DESIGN: Degeneration was induced in t...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Gullbrand, Sarah E., Malhotra, Neil R., Schaer, Thomas P., Zawacki, Zosia, Martin, John T., Bendigo, Justin R., Milby, Andrew H., Dodge, George R., Vresilovic, Edward J., Elliott, Dawn M., Mauck, Robert L., Smith, Lachlan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182186/
https://ncbi.nlm.nih.gov/pubmed/27568573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.08.006
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