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C-Myb(+) Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

Although classified as hematopoietic cells, tissue- resident macrophages (MFs) arise from embryonic precursors that seed the tissues prior to birth to generate a self-renewing population, which is maintained independently of adult hematopoiesis. Here we reveal the identity of these embryonic precurs...

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Bibliographic Details
Published in:Immunity
Main Authors: Hoeffel, Guillaume, Chen, Jinmiao, Lavin, Yonit, Low, Donovan, Almeida, Francisca F., See, Peter, Beaudin, Anna E., Lum, Josephine, Low, Ivy, Forsberg, E. Camilla, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Ng, Lai Guan, Chan, Jerry K.Y., Greter, Melanie, Becher, Burkhard, Samokhvalov, Igor M., Merad, Miriam, Ginhoux, Florent
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545768/
https://ncbi.nlm.nih.gov/pubmed/25902481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.011
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