C-Myb(+) Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

Although classified as hematopoietic cells, tissue- resident macrophages (MFs) arise from embryonic precursors that seed the tissues prior to birth to generate a self-renewing population, which is maintained independently of adult hematopoiesis. Here we reveal the identity of these embryonic precurs...

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Gepubliceerd in:Immunity
Hoofdauteurs: Hoeffel, Guillaume, Chen, Jinmiao, Lavin, Yonit, Low, Donovan, Almeida, Francisca F., See, Peter, Beaudin, Anna E., Lum, Josephine, Low, Ivy, Forsberg, E. Camilla, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Ng, Lai Guan, Chan, Jerry K.Y., Greter, Melanie, Becher, Burkhard, Samokhvalov, Igor M., Merad, Miriam, Ginhoux, Florent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545768/
https://ncbi.nlm.nih.gov/pubmed/25902481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.03.011
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